Description
gamma-Linolenic acid is an unsaturated fatty acid synthesized from linoleic acid (LA) by the enzyme delta-6-desaturase. Research on hepatocellular cell lines has shown gamma-Linolenic Acid to have induced reactive oxygen species generation including lipid peroxidation cell growth inhibition and heme oxygenase-1 production for antioxidant protection against oxidative stress. Further experiments have noted that gamma-Linolenic acid inhibits inflammatory responses through inactivation of NFkappaB and activator protein-1 by suppressed oxidative stress